Advice #1: turn the caps-lock off.
Other general rules of advice...
Get a good starting hand selection system. In general, you want cards that play well with each other. Since there are 6 different combinations of two cards from your starting four, you want them all to play together well. For example...
AhAdKhQd is a strong opening hand. You've got a high pair (for trips and boats), double suited twice (for flushes), and the cards are close together (for str8s). A "co-ordinated" hand is what you're looking for.
In a full game I've found the following rules of the thumb keep me out of trouble...
- If the board has paired, someone has a boat.
- If there are three of the same suit on the board, someone has a flush.
- If there are neither, someone has a straight.
- Two pair is a losing hand in PLO.
Stuff the pot with the nuts, draw to the nuts if you're getting the right price, fold everything else.
This advice is EXCEEDINGLY generalized, but a good starting point for the beginning PLO player.
Good luck, Perry!